The best antibiotic for strep throat in adults should deliver the most optimal balance between the effectiveness, convenience, safety, and cost. Keep in mind that antibiotic choices would depend mostly on the allergies of the patients, clinical effectiveness, duration, potential side effects, and cost. Strep throat is caused by bacteria, which means you or your child have antibiotics you can take to treat it. Strep throat in adults can present itself in several variations. Generally speaking, it is a bacterial infection that occurs in the throat and tonsils. Streptococcal bacteria can cause strep throat, irritation and inflammation. While strep does cause pain in the throat, sore throats are typically viral infections and. Antibiotics for treatment of strep throat with dosage for adults and children, including amoxicillin, penicillin, azithromycin, cefuroxime learn which antibiotics dont work for streptococcal pharyngitis. Updated according to 2012 idsa guideline for managing group a streptococcal pharyngitis and now includes clindamycin. Most of these antibiotics come in a liquid form that will be easier for children to take. The best antibiotic for a strep throat will depend on many patient-specific factors, such as allergies, tolerance to medications, ability to swallow tablets, resistance patterns, and cost concerns. Best antibiotics for strep throat antibiotics are the best way to get rid of strep throat. So if youre worried you or your child may have strep throat its important to know which antibiotics are going to get the job done. Read on to learn which antibiotics are typically prescribed for strep throat.