Strange aching, sore spot deep in left front neckthroat by guest 278 posts, last post 20 days ago dhruv gupta, md answered this sore spot and pain deep in the neck. Doctors give trusted, helpful answers on causes, diagnosis, symptoms, treatment, and more dr. Puppala on deep sore throat pain sore throat can be caused by virus or bacteria. I would recommend that you see a doctor and get a rapid strep and culture. If it is strep, you will need a prescription for an antibiotic. In the meantime there are lots of soothing otc lozenges for relief of pain. Its not uncommon to experience a stiff neck along with a sore throat. Learn how these symptoms are related, what causes them, and how to treat them. When any of these areas become infected or disturbed, the result can be a painful neck and sore throat. In rare cases, a sore throat can be a sign of a serious illness, but most neck and throat pain is bacterial or viral in nature and can be treated at home or with a prescription for antibiotics. Most of the time, it is a symptom of allergies, a cold, or the flu. While a sore throat can be painful, it is usually not serious. Pain in the front of the neck is often caused by a sore throat or muscle strain and will go away on its own. But if you think youre having a heart attack, seek medical help immediately. Mononucleosis is a viral infection that causes fever, sore throats and inflamed lymph nodes in the neck 2. The symptoms can be severe, with a sore throat that causes pain throughout the neck and lymph nodes that can be so inflamed that patients can barely move their neck. Lymph nodes in the neck can become painful for a variety of reasons, including infectious and noninfectious. Read more below to learn about associated symptoms, possible causes, and treatment options for painful lymph nodes in the neck.