If you are having pain with breathing, whether normal breathing or when taking a deep breath, youre likely feeling worried. Doctors describe the kind of pain that occurs with taking a deep breath as either pleuritic chest pain or pleurisy. 5 conditions that may cause tightness in throat and chest experiencing symptoms like this can be troubling, and cause impairment in ones ability to carry out day-to-day task. I get deep and sharp pain in throatchest when breathing in deep feels like its from the esophagus, any ideas? Chest pain is the common symptom of this condition and it worsens with movements, slight pressure, and deep breathing. Certain medical conditions that affect the ribs may also cause chest pain, which may worsen with deep inhalation. The combination of sore throat and chest pain could be a sign of asthma, gerd, lung cancer, or another underlying condition. Learn more about these potential conditions and how theyre diagnosed. This chest pain when inhaling deeply can occur during or after exercise or when moving, during sleep (especially supine sleep, but also when lying on the left or right sides), after meals (overeating and large meals intensify breathing), due to stress and deep breathing.